Protein Details: Potassium voltage-gated channel subfamily V member 1
Protein ID
ICDB_Pro_1501
Protein Name
Potassium voltage-gated channel subfamily V member 1
Gene Name
KCNV1; QccE-20536
Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Length
500 amino acids
AlphaFoldDB
AF-Q9GKU7-F1-model_v4.pdb
Function
Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1; KCNB2; KCNC4 and KCND1; possibly by trapping them in intracellular membranes (By similarity)
Sequence
MPSSGRALLDSPLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDSYISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF
PDB Structures
Ligand Binding
Binding Site
Disease
Location
DOI ID
RefSeq
NP_001274541.1; XP_005564006.1